验证数据展示
产品信息
67974-1-PBS targets LIMK1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
Tested Applications | WB, IHC, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat, pig, rabbit |
Immunogen | LIMK1 fusion protein Ag28862 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | LIM domain kinase 1 |
Synonyms | LIMK-1, LIMK 1, LIMK, LIM domain kinase 1, EC:2.7.11.1 |
Calculated Molecular Weight | 647 aa, 73 kDa |
Observed Molecular Weight | 65 kDa |
GenBank Accession Number | BC152982 |
Gene Symbol | LIMK1 |
Gene ID (NCBI) | 3984 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P53667 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
LIMK1,also named LIMK, belongs to the protein kinase superfamily and TKL Ser/Thr protein kinase family. LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. LIMK1 may be involved in brain development. The antibody has no cross-reaction with LIMK2.