LPCAT2 Monoclonal antibody, PBS Only
LPCAT2 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1E6G1
验证数据展示
产品信息
68476-1-PBS targets LPCAT2 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | Human, mouse, rat |
| Immunogen | LPCAT2 fusion protein Ag26420 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | lysophosphatidylcholine acyltransferase 2 |
| Synonyms | Acyltransferase like 1, AYTL1, DKFZp686H22112, FLJ20481, LPC acyltransferase 2, LPCAT 2, LPCAT2, Lyso PAF acetyltransferase, LysoPAFAT, LysoPC acyltransferase 2 |
| Calculated Molecular Weight | 60 kDa |
| Observed Molecular Weight | 68 kDa |
| GenBank Accession Number | BC002472 |
| Gene Symbol | LPCAT2 |
| Gene ID (NCBI) | 54947 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q7L5N7 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
LPCAT2 (Lysophosphatidylcholine acyltransferase 2) is also named as AGPAT11 and AYTL1. Lipid droplet (LD) content of CRC cells positively correlates with the expression of lysophosphatidylcholine acyltransferase 2 (LPCAT2), an LD-localised enzyme supporting phosphatidylcholine synthesis (PMID: 29358673). Mitochondria play a significant role in ACSL4/LPCAT2-driven ferroptosis (PMID: 3762584). In response to LPS, LPCAT2, but not LPCAT1, rapidly associates with TLR4 and translocates to membrane lipid raft domains to regulate macrophage inflammatory gene expression (PMID: 32587324).