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Anti-Human LRP1 (5A6)

LRP1 Monoclonal Antibody for FC

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

FC

Conjugate

Unconjugated

CloneNo.

5A6

Cat no : 65233-1-Ig

Print datasheet

Synonyms

A2MR, Alpha 2 macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, CD91, FLJ16451, IGFBP3R, LRP, LRP 1, LRP1, LRPICD, TGFBR5

验证数据展示

  • FC experiment of U-87 MG using 65233-1-Ig

    FC experiment of U-87 MG using 65233-1-Ig

    1X10^6 U-87 MG cells were surface stained with 1 ug Anti-Human LRP1 (65233-1-Ig, Clone:5A6) and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (red), or 1 ug Control Antibody. Cells were not fixed.

经过测试的应用

Positive FC detected inU-87 MG cells

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

65233-1-Ig targets LRP1 in FC applications and shows reactivity with Human samples.

Tested Applications FC Application Description
Tested Reactivity Human
Immunogen Full length native protein (purified) 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
Synonyms A2MR, Alpha 2 macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, CD91, FLJ16451, IGFBP3R, LRP, LRP 1, LRP1, LRPICD, TGFBR5
Calculated Molecular Weight 505 kDa
GenBank Accession NumberBC045107
Gene Symbol LRP1
Gene ID (NCBI) 4035
RRIDAB_3084909
Conjugate Unconjugated
Form Liquid
Purification MethodAffinity purification
UNIPROT IDQ07954
Storage Buffer PBS with 0.09% sodium azide.
Storage ConditionsStore at 2-8°C. Stable for one year after shipment.

背景介绍

LRP1 (Prolow-density lipoprotein receptor-related protein 1), also known as A2MR, APOER and CD91, is a type I transmembrane protein that belongs to the LDLR family. LRP1 is synthesized as a transmembrane glycosylated precursor of 600 kDa, and is subsequently cleaved to generate a large 515-kDa N-terminal extracellular subunit and an 85-kDa C-terminal transmembrane subunit, which are noncovalently associated with one another (PMID: 2112085; 8546712). LRP1 is a multifunctional receptor involved in the clearance of a large number of diverse ligands and modulating various cellular processes. LRP1 is implicated in conditions such as atherosclerosis, cancer and neurodegenerative diseases (PMID: 28381441).

实验方案

Product Specific Protocols
FC protocol for LRP1 antibody 65233-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols