Anti-Human LRP1 (5A6)

LRP1 Monoclonal Antibody for FC
Cat No. 65233-1-Ig

产品说明书

CloneNo. 5A6

宿主/亚型

Mouse / IgG2b

种属反应性

Human

应用

FC

A2MR, Alpha 2 macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, CD91, FLJ16451, IGFBP3R, LRP, LRP 1, LRP1, LRPICD, TGFBR5

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inU-87 MG cells

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

65233-1-Ig targets LRP1 in FC applications and shows reactivity with Human samples.

经测试应用 FC Application Description
经测试反应性 Human
免疫原 Full length native protein (purified) 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
别名 A2MR, Alpha 2 macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, CD91, FLJ16451, IGFBP3R, LRP, LRP 1, LRP1, LRPICD, TGFBR5
计算分子量 505 kDa
GenBank蛋白编号BC045107
基因名称 LRP1
Gene ID (NCBI) 4035
RRIDAB_3084909
偶联类型 Unconjugated
形式 Liquid
纯化方式Affinity purification
UNIPROT IDQ07954
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Stable for one year after shipment.

背景介绍

LRP1 (Prolow-density lipoprotein receptor-related protein 1), also known as A2MR, APOER and CD91, is a type I transmembrane protein that belongs to the LDLR family. LRP1 is synthesized as a transmembrane glycosylated precursor of 600 kDa, and is subsequently cleaved to generate a large 515-kDa N-terminal extracellular subunit and an 85-kDa C-terminal transmembrane subunit, which are noncovalently associated with one another (PMID: 2112085; 8546712). LRP1 is a multifunctional receptor involved in the clearance of a large number of diverse ligands and modulating various cellular processes. LRP1 is implicated in conditions such as atherosclerosis, cancer and neurodegenerative diseases (PMID: 28381441).

实验方案

Product Specific Protocols
FC protocol for LRP1 antibody 65233-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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