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验证数据展示

  • FC experiment of U-87 MG using CL594-65233

    FC experiment of U-87 MG using CL594-65233

    1x10^6 U-87 MG cells were surface stained with 5 ul CoraLite® Plus 594 Anti-Human LRP1 (CL594-65233, Clone:5A6) or CoraLite®594 Mouse IgG2b Isotype Control (CL594-65128, Clone: MPC-11). Cells were not fixed.

  • FC experiment of U-87 MG using CL594-65233

    FC experiment of U-87 MG using CL594-65233

    1x10^6 U-87 MG cells were surface stained with 5 ul CoraLite® Plus 594 Anti-Human LRP1 (CL594-65233, Clone:5A6) or CoraLite®594 Mouse IgG2b Isotype Control (CL594-65128, Clone: MPC-11). Cells were not fixed.

CoraLite® Plus 594 Anti-Human LRP1 (5A6)

LRP1 Monoclonal Antibody for FC
Cat No. CL594-65233

Print datasheet

CloneNo. 5A6

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

FC

Synonyms

Apolipoprotein E receptor, APOER, Alpha-2-macroglobulin receptor, Alpha 2 macroglobulin receptor, A2MR

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  CoraLite® Plus 594
Size: 

-/ -

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经过测试的应用

Positive FC detected inU-87 MG cells
For other applications, we recommend the unconjugated version of this antibody, 65233-1-Ig

推荐稀释比

ApplicationDilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-65233 targets LRP1 in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Full length native protein (purified) 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
Synonyms Apolipoprotein E receptor, APOER, Alpha-2-macroglobulin receptor, Alpha 2 macroglobulin receptor, A2MR
Calculated Molecular Weight 505 kDa
GenBank Accession NumberBC045107
Gene Symbol LRP1
Gene ID (NCBI) 4035
Conjugate CoraLite® Plus 594 Fluorescent Dye
Excitation/Emission Maxima Wavelengths594 nm / 615 nm
Form Liquid
Purification MethodN/A
UNIPROT IDQ07954
Storage Buffer PBS with 0.09% sodium azide and 0.5% BSA.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

LRP1 (Prolow-density lipoprotein receptor-related protein 1), also known as A2MR, APOER and CD91, is a type I transmembrane protein that belongs to the LDLR family. LRP1 is synthesized as a transmembrane glycosylated precursor of 600 kDa, and is subsequently cleaved to generate a large 515-kDa N-terminal extracellular subunit and an 85-kDa C-terminal transmembrane subunit, which are noncovalently associated with one another (PMID: 2112085; 8546712). LRP1 is a multifunctional receptor involved in the clearance of a large number of diverse ligands and modulating various cellular processes. LRP1 is implicated in conditions such as atherosclerosis, cancer and neurodegenerative diseases (PMID: 28381441).

实验方案

Product Specific Protocols
FC protocol for CL Plus 594 LRP1 antibody CL594-65233Download protocol
Standard Protocols
Click here to view our Standard Protocols