• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of U-87 MG using CR-65233

    FC experiment of U-87 MG using CR-65233

    1X10^6 U-87 MG cells were surface stained with 5 ul Cardinal Red™ Anti-Human LRP1 (CR-65233, Clone:5A6), or Mouse IgG2b Isotype Control. Cells were not fixed.

  • FC experiment of U-87 MG using CR-65233

    FC experiment of U-87 MG using CR-65233

    1X10^6 U-87 MG cells were surface stained with 5 ul Cardinal Red™ Anti-Human LRP1 (CR-65233, Clone:5A6), or Mouse IgG2b Isotype Control. Cells were not fixed.

Cardinal Red™ Anti-Human LRP1 (5A6)

LRP1 Monoclonal Antibody for FC
Cat No. CR-65233

产品说明书

CloneNo. 5A6

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

FC

别名

A2MR, Alpha 2 macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, CD91, FLJ16451, IGFBP3R, LRP, LRP 1, LRP1, LRPICD, TGFBR5

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Cardinal Red™
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

经过测试的应用

Positive FC detected inU-87 MG cells

推荐稀释比

应用推荐稀释比
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

CR-65233 targets LRP1 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Full length native protein (purified) 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
别名 A2MR, Alpha 2 macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, CD91, FLJ16451, IGFBP3R, LRP, LRP 1, LRP1, LRPICD, TGFBR5
计算分子量 505 kDa
GenBank蛋白编号BC045107
基因名称 LRP1
Gene ID (NCBI) 4035
RRIDAB_3084983
偶联类型 Cardinal Red™ Fluorescent Dye
最大激发/发射波长592 nm / 611 nm
形式 Liquid
纯化方式N/A
UNIPROT IDQ07954
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

LRP1 (Prolow-density lipoprotein receptor-related protein 1), also known as A2MR, APOER and CD91, is a type I transmembrane protein that belongs to the LDLR family. LRP1 is synthesized as a transmembrane glycosylated precursor of 600 kDa, and is subsequently cleaved to generate a large 515-kDa N-terminal extracellular subunit and an 85-kDa C-terminal transmembrane subunit, which are noncovalently associated with one another (PMID: 2112085; 8546712). LRP1 is a multifunctional receptor involved in the clearance of a large number of diverse ligands and modulating various cellular processes. LRP1 is implicated in conditions such as atherosclerosis, cancer and neurodegenerative diseases (PMID: 28381441).

实验方案

Product Specific Protocols
FC protocol for Cardinal Red™ LRP1 antibody CR-65233Download protocol
Standard Protocols
Click here to view our Standard Protocols