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METTL1 Monoclonal antibody, PBS Only

METTL1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, mouse, pig

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2C3G7

Cat no : 68501-1-PBS

Print datasheet

Synonyms

C12orf1, FLJ95748, methyltransferase like 1, METTL1, TRM8, tRNA(m7G46) methyltransferase, YDL201w

验证数据展示

  • WB analysis using 68501-1-Ig (same clone as 68501-1-PBS)

    WB analysis using 68501-1-Ig (same clone as 68501-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68501-1-Ig (METTL1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68501-1-PBS in a different storage buffer formulation.

  • WB analysis using 68501-1-Ig (same clone as 68501-1-PBS)

    WB analysis using 68501-1-Ig (same clone as 68501-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68501-1-Ig (METTL1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68501-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy METTL1 Ready-To-Use IHC Kit. METTL1 primary antibody included.

产品信息

68501-1-PBS targets METTL1 in WB, ELISA applications and shows reactivity with Human, mouse, pig samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human, mouse, pig
Immunogen METTL1 fusion protein Ag7055 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name methyltransferase like 1
Synonyms C12orf1, FLJ95748, methyltransferase like 1, METTL1, TRM8, tRNA(m7G46) methyltransferase, YDL201w
Calculated Molecular Weight 31 kDa
Observed Molecular Weight31 kDa
GenBank Accession NumberBC000550
Gene Symbol METTL1
Gene ID (NCBI) 4234
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9UBP6
Storage Buffer PBS only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

METTL1 methyltransferase mediates m7G methylation within miRNAs and regulates cell migration via its catalytic activity. METTL1 can be inactivated by phosphorylation at Ser27 by protein kinase B (PKBα). Overexpression of METTL1 is widely observed among human cancers. It is also crucial for the regulation of chemoresistance in cancer treatment. In addition, mutations in the human N7-methylguanosine (m7G) methyltransferase complex METTL1/WDR4 cause primordial dwarfism and brain malformation.