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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 68501-1-Ig (same clone as 68501-1-PBS)

    WB analysis using 68501-1-Ig (same clone as 68501-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68501-1-Ig (METTL1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68501-1-PBS in a different storage buffer formulation.

  • WB analysis using 68501-1-Ig (same clone as 68501-1-PBS)

    WB analysis using 68501-1-Ig (same clone as 68501-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68501-1-Ig (METTL1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68501-1-PBS in a different storage buffer formulation.

METTL1 Monoclonal antibody, PBS Only

METTL1 Monoclonal Antibody for WB, ELISA
Cat No. 68501-1-PBS

产品说明书

CloneNo. 2C3G7

宿主/亚型

Mouse / IgG2a

种属反应性

Human, mouse, pig

应用

WB, ELISA

别名

C12orf1, FLJ95748, methyltransferase like 1, METTL1, TRM8, tRNA(m7G46) methyltransferase, YDL201w

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy METTL1 Ready-To-Use IHC Kit. METTL1 primary antibody included.

产品信息

68501-1-PBS targets METTL1 in WB, ELISA applications and shows reactivity with Human, mouse, pig samples.

经测试应用 WB, ELISA Application Description
经测试反应性 Human, mouse, pig
免疫原 METTL1 fusion protein Ag7055 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 methyltransferase like 1
别名 C12orf1, FLJ95748, methyltransferase like 1, METTL1, TRM8, tRNA(m7G46) methyltransferase, YDL201w
计算分子量 31 kDa
观测分子量31 kDa
GenBank蛋白编号BC000550
基因名称 METTL1
Gene ID (NCBI) 4234
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9UBP6
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

METTL1 methyltransferase mediates m7G methylation within miRNAs and regulates cell migration via its catalytic activity. METTL1 can be inactivated by phosphorylation at Ser27 by protein kinase B (PKBα). Overexpression of METTL1 is widely observed among human cancers. It is also crucial for the regulation of chemoresistance in cancer treatment. In addition, mutations in the human N7-methylguanosine (m7G) methyltransferase complex METTL1/WDR4 cause primordial dwarfism and brain malformation.