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  • Featured Product
  • KD/KO Validated

MTCO2 Monoclonal antibody, PBS Only

MTCO2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

10G14F4

Cat no : 68527-1-PBS

Print datasheet

Synonyms

COX2, MT CO2, COXII, COX 2, COII

验证数据展示

  • WB analysis of 143B.TK.P0 using 68527-1-Ig (same clone as 68527-1-PBS)

    WB analysis of 143B.TK.P0 using 68527-1-Ig (same clone as 68527-1-PBS)

    WB result of MTCO2 antibody (MTCO2; 1:1000; incubated at room temperature for 1.5 hours) with 143B and 143B.TK.ρ0 cell. 143B is wild-type cell line, 143B.TK.ρ0 is mtDNA deletion cell line. This data was developed using the same antibody clone with 68527-1-PBS in a different storage buffer formulation.

  • WB analysis using 68527-1-Ig (same clone as 68527-1-PBS)

    WB analysis using 68527-1-Ig (same clone as 68527-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68527-1-Ig (MTCO2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68527-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy MTCO2/COX2 Ready-To-Use IHC Kit. MTCO2/COX2 primary antibody included.

产品信息

68527-1-PBS targets MTCO2 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Peptide 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name cytochrome c oxidase II
Synonyms COX2, MT CO2, COXII, COX 2, COII
Calculated Molecular Weight 26 kDa
Observed Molecular Weight 23-26 kDa
GenBank Accession NumberYP_003024029
Gene Symbol MTCO2
Gene ID (NCBI) 4513
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP00403
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MTCO2, also named as COII, COXII, and COX2, belongs to the cytochrome c oxidase subunit 2 family. It is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. Defects in COX2 are a cause of mitochondrial complex IV deficiency (MT-C4D).