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MYBPC3 Monoclonal antibody, PBS Only

MYBPC3 Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, pig, rabbit

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3C8F8

Cat no : 67608-1-PBS

Print datasheet

Synonyms

Cardiac MyBP C, CMH4, DKFZp779E1762, FHC, MYBP C, MYBPC3

验证数据展示

  • IHC staining of human heart using 67608-1-Ig (same clone as 67608-1-PBS)

    IHC staining of human heart using 67608-1-Ig (same clone as 67608-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 67608-1-Ig (MYBPC3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67608-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse heart using 67608-1-Ig (same clone as 67608-1-PBS)

    WB analysis of mouse heart using 67608-1-Ig (same clone as 67608-1-PBS)

    mouse heart tissue were subjected to SDS PAGE followed by western blot with 67608-1-Ig (MYBPC3 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67608-1-PBS in a different storage buffer formulation.

  • IF Staining of rat heart using 67608-1-Ig (same clone as 67608-1-PBS)

    IF Staining of rat heart using 67608-1-Ig (same clone as 67608-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed rat heart tissue using MYBPC3 antibody (67608-1-Ig, Clone: 3C8F8 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67608-1-PBS in a different storage buffer formulation.

产品信息

67608-1-PBS targets MYBPC3 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig, rabbit samples.

Tested Applications WB, IHC, IF-P, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, pig, rabbit
Immunogen MYBPC3 fusion protein Ag15848 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name myosin binding protein C, cardiac
Synonyms Cardiac MyBP C, CMH4, DKFZp779E1762, FHC, MYBP C, MYBPC3
Calculated Molecular Weight 1274 aa, 141 kDa
Observed Molecular Weight 140-150 kDa
GenBank Accession NumberBC151211
Gene Symbol MYBPC3
Gene ID (NCBI) 4607
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ14896
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MYBPC3 belongs to the immunoglobulin superfamily and MyBP family. MYBPC3 located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Defects in MYBPC3 are the cause of cardiomyopathy familial hypertrophic type 4 (CMH4).