CoraLite®594-conjugated MYBPC3 Monoclonal antibody
MYBPC3 Monoclonal Antibody for WB
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat, pig
Applications
WB
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
3C8F8
验证数据展示
经过测试的应用
Positive WB detected in | rat heart tissue, mouse heart tissue |
For other applications, we recommend the unconjugated version of this antibody, 67608-1-Ig
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:2000-1:16000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL594-67608 targets MYBPC3 in WB applications and shows reactivity with Human, mouse, rat, pig samples.
Tested Applications | WB Application Description |
Tested Reactivity | Human, mouse, rat, pig |
Immunogen | MYBPC3 fusion protein Ag15848 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | myosin binding protein C, cardiac |
Synonyms | Cardiac MyBP C, CMH4, DKFZp779E1762, FHC, MYBP C, MYBPC3 |
Calculated Molecular Weight | 1274 aa, 141 kDa |
Observed Molecular Weight | 140-150 kDa |
GenBank Accession Number | BC151211 |
Gene Symbol | MYBPC3 |
Gene ID (NCBI) | 4607 |
Conjugate | CoraLite®594 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q14896 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MYBPC3 belongs to the immunoglobulin superfamily and MyBP family. MYBPC3 located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Defects in MYBPC3 are the cause of cardiomyopathy familial hypertrophic type 4 (CMH4).
实验方案
Product Specific Protocols | |
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WB protocol for CL594 MYBPC3 antibody CL594-67608 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |