CoraLite®594-conjugated MLPH Monoclonal antibody

MLPH Monoclonal Antibody for IF/ICC
Cat No. CL594-66092

产品说明书

CloneNo. 1A8D12

宿主/亚型

Mouse / IgG1

种属反应性

human, pig

应用

IF/ICC

SlaC2-a, SLAC2A, SLAC2 A, Melanophilin, Exophilin-3

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inHepG2 cells
For other applications, we recommend the unconjugated version of this antibody, 66092-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-66092 targets MLPH in IF/ICC applications and shows reactivity with human, pig samples.

经测试应用 IF/ICC Application Description
经测试反应性 human, pig
免疫原 MLPH fusion protein Ag19286 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 melanophilin
别名 SlaC2-a, SLAC2A, SLAC2 A, Melanophilin, Exophilin-3
计算分子量 66 kDa
观测分子量 66 kDa
GenBank蛋白编号BC001653
基因名称 MLPH
Gene ID (NCBI) 79083
RRIDAB_2883507
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ9BV36
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Melanophilin (MLPH) is a member of the exophilin subfamily of Rab effector proteins. MLPH is a modular protein, forming a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. It regulates retention of melanosomes at the peripheral actin cytoskeleton of melanocytes, a process essential for normal mammalian pigmentation. Defects in MLPH are a cause of Griscelli syndrome type 3 (GS3), which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft.

实验方案

Product Specific Protocols
IF protocol for CL594 MLPH antibody CL594-66092Download protocol
Standard Protocols
Click here to view our Standard Protocols
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