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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84879-5-RR (same clone as 84879-5-PBS)

    WB analysis using 84879-5-RR (same clone as 84879-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84879-5-RR (Methylmalonyl Coenzyme A mutase/MUT antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84879-5-PBS in a different storage buffer formulation.

  • FC experiment of A431 using 84879-5-RR (same clone as 84879-5-PBS)

    FC experiment of A431 using 84879-5-RR (same clone as 84879-5-PBS)

    1x10^6 A431 cells were intracellularly stained with 0.25 ug Methylmalonyl Coenzyme A mutase/MUT Recombinant antibody (84879-5-RR, Clone:242198F11) and APC-Conjugated Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 84879-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84879-5-RR

    Affinity and Kinetic Characterization of 84879-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84879-5-RR against Human Methylmalonyl Coenzyme A mutase/MUT were performed. The affinity constant is 1.83 nM.

Methylmalonyl Coenzyme A mutase/MUT Recombinant antibody, PBS Only

Methylmalonyl Coenzyme A mutase/MUT Uni-rAbTM Recombinant Antibody for WB, FC (Intra), Indirect ELISA
Cat No. 84879-5-PBS

产品说明书

CloneNo. 242198F11

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, FC (Intra), Indirect ELISA

别名

MUT, Methylmalonyl-CoA isomerase, Methylmalonyl Coenzyme A mutase, Methylmalonyl CoA isomerase, MCM

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 
100 μg

¥5800/ 100 μg

浓度: 1 mg/ml

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Planning an IHC experiment? We recommend our IHCeasy MUT Ready-To-Use IHC Kit. MUT primary antibody included.

产品信息

84879-5-PBS targets Methylmalonyl Coenzyme A mutase/MUT in WB, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, FC (Intra), Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Methylmalonyl Coenzyme A mutase/MUT fusion protein Ag10523 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 methylmalonyl Coenzyme A mutase
别名 MUT, Methylmalonyl-CoA isomerase, Methylmalonyl Coenzyme A mutase, Methylmalonyl CoA isomerase, MCM
计算分子量 750 aa, 83 kDa
观测分子量 78 kDa
GenBank蛋白编号BC016282
基因名称 MUT
Gene ID (NCBI) 4594
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP22033
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Methylmalonyl Coenzyme A mutase (MUT) is an enzyme that plays a crucial role in the metabolism of certain amino acids and fatty acids. Mutations in the MUT gene can lead to methylmalonic acidemia, a metabolic disorder characterized by the accumulation of toxic compounds such as methylmalonyl-CoA and propionyl-CoA. This condition can cause severe health issues including developmental delays, metabolic acidosis, and neurological problems. MUT is essential for maintaining normal metabolic processes and its dysfunction can have significant health implications, highlighting its importance in both basic metabolism and clinical medicine.