Midkine Recombinant antibody, PBS Only
Midkine Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
241880H1
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy MDK Ready-To-Use IHC Kit. MDK primary antibody included.
产品信息
84815-1-PBS targets Midkine in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | Midkine fusion protein Ag24547 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | midkine (neurite growth-promoting factor 2) |
Synonyms | MDK, Neurite outgrowth-promoting protein, Neurite outgrowth-promoting factor 2, Amphiregulin-associated protein, 241880H1 |
Calculated Molecular Weight | 16 kDa |
GenBank Accession Number | BC011704 |
Gene Symbol | Midkine |
Gene ID (NCBI) | 4192 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P21741 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Midkine is a heparin-binding growth factor identified over 20 years ago and enhances the survival, migration and many other activities of target cells. Midkine is rich in both basic amino acids and cysteine, and is not related to most other growth factors/cytokines. It is strongly expressed during embryonic periods, especially at the midgestation stage, and plays important roles in development, especially in neurogenesis. Midkine expression in adult tissue is generally weak or undetectable, and it is induced upon injury and exerts many activities related to tissue repair. The biological activities of midkine in malignant tumors include proliferation, angiogenesis, invasion and metastasis. Various cancers express significantly higher levels of the midkine protein in early stage tumor tissues than in adjacent normal tissue.