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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 83494-6-RR (same clone as 83494-6-PBS)

    WB analysis using 83494-6-RR (same clone as 83494-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83494-6-RR (NCAM2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83494-6-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 83494-6-RR (same clone as 83494-6-PBS)

    IF Staining of mouse brain using 83494-6-RR (same clone as 83494-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using NCAM2 antibody (83494-6-RR, Clone: 240398D9 ) at dilution of 1:500 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83494-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83494-6-RR

    Affinity and Kinetic Characterization of 83494-6-RR

    Biolayer interferometry (BLl) kinetic assays of 83494-6-RR against Human NCAM2 were performed. The affinity constant is 4.48 nM.

NCAM2 Recombinant antibody, PBS Only

NCAM2 Uni-rAbTM Recombinant Antibody for WB, IF-P, ELISA
Cat No. 83494-6-PBS

产品说明书

CloneNo. 240398D9

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF-P, ELISA

别名

NCAM21, NCAM-2, NCAM 2, N CAM 2, 240398D9

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

83494-6-PBS targets NCAM2 in WB, IF-P, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF-P, ELISA Application Description
经测试反应性 human, mouse
免疫原 NCAM2 fusion protein Ag4821 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 neural cell adhesion molecule 2
别名 NCAM21, NCAM-2, NCAM 2, N CAM 2, 240398D9
计算分子量 93 kDa
观测分子量125 kDa
GenBank蛋白编号BC052946
基因名称 NCAM2
Gene ID (NCBI) 4685
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDO15394
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The mammalian NCAM family has two members, NCAM1 and NCAM2 (PMID: 9729879; 20439718). Neural cell adhesion molecule 2 (NCAM2, also known as NCAM21) is a single-pass type I membrane protein that is highly expressed in the brain, which may play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons or in neurodegenerative diseases such as Alzheimer's disease (PMID: 26611261). NCAM2 has two isoforms: NCAM2.1 bearing transmembrane and cytoplasmic domains and the shorter NCAM2.2 isoform, which is GPI-anchored (PMID: 9334170; 9221781). The molecular weight of NCAM2 is around 125 kDa and 93 kDa (PMID: 9334170; 3171685).