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验证数据展示

  • WB analysis of human testis using 13069-1-AP (same clone as 13069-1-PBS)

    WB analysis of human testis using 13069-1-AP (same clone as 13069-1-PBS)

    human testis tissue were subjected to SDS PAGE followed by western blot with 13069-1-AP (NKX3-1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13069-1-PBS in a different storage buffer formulation.

  • WB analysis of LNCaP using 13069-1-AP (same clone as 13069-1-PBS)

    WB analysis of LNCaP using 13069-1-AP (same clone as 13069-1-PBS)

    LNCaP cells were subjected to SDS PAGE followed by western blot with 13069-1-AP (NKX3-1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13069-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 13069-1-AP (same clone as 13069-1-PBS)

    IHC staining of human prostate cancer using 13069-1-AP (same clone as 13069-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 13069-1-AP (NKX3-1 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13069-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with NKX3.1 antibody included
  • IHC staining of human prostate cancer using 13069-1-AP (same clone as 13069-1-PBS)

    IHC staining of human prostate cancer using 13069-1-AP (same clone as 13069-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 13069-1-AP (NKX3-1 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13069-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with NKX3.1 antibody included

NKX3-1 Polyclonal antibody, PBS Only

NKX3-1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 13069-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy NKX3.1 Ready-To-Use IHC Kit. NKX3.1 primary antibody included.

产品信息

13069-1-PBS targets NKX3-1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 NKX3-1 fusion protein Ag4070 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 NK3 homeobox 1
别名
计算分子量 234 aa, 26 kDa
观测分子量34-38 kDa
GenBank蛋白编号BC074864
基因名称 NKX3-1
Gene ID (NCBI) 4824
RRIDAB_10640580
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ99801
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NKX3-1, also named as NKX3.1 and NKX3A, belongs to the NK-3 homeobox family. It is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. NKX3-1 plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. It act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells(PMID:19462257). The calcualted molecular weight of NKX3-1 is 26 kDa, but modified NKX3-1 is about 32-35 kDa. (PMID: 18597829)