NUPR1 Recombinant antibody

NUPR1 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 83315-2-RR

产品说明书

CloneNo. 240149G4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

NUPR 1, Nuclear protein 1, COM1, 240149G4

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inNCI-H1299 cells
Planning an IHC experiment? We recommend our IHCeasy NUPR1 Ready-To-Use IHC Kit. NUPR1 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

83315-2-RR targets NUPR1 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 NUPR1 fusion protein Ag7039 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 nuclear protein 1
别名 NUPR 1, Nuclear protein 1, COM1, 240149G4
计算分子量 8 kDa
观测分子量10 kDa
GenBank蛋白编号BC002434
基因名称 NUPR1
Gene ID (NCBI) 26471
RRIDAB_3670981
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO60356
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

NUPR1, also named as COM1 and P8, is a small nuclear protein that is responsive to various stress stimuli. NUPR1 can be induced by hypoxia, oxidative stress, while the expression is low in physiological condition. It is associated with chemoresistance in multiple malignancies. The predicted MW of NUPR1 is 8 kDa, it also has another isoform of 10 kDa and we also detectet bands around 17 and 38 kDa, which are similar to the papers(PMID: 29130426, 27336713, 28694771, 22961798). NUPR1 was also found in a complex with ANXA2, TRIM21, YBX1, S100A9, HSPA8, HSPA9, HSPA4, HSPA5, and ESR1, suggesting that these proteins might play a role in its functional regulation (PMID: 33542201), and it can also form a complex with PADI4 and plays crucial functions in modulating DNA-repair, favoring metastasis, or facilitating citrullination of other proteins (PMID: 36858171).

实验方案

Product Specific Protocols
WB protocol for NUPR1 antibody 83315-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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