CoraLite®594-conjugated Neuropilin 1 Monoclonal antibody
Neuropilin 1 Monoclonal Antibody for FC (Intra)
Host / Isotype
Mouse / IgG1
Reactivity
human, pig
Applications
FC (Intra)
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
2H3F6
验证数据展示
经过测试的应用
| Positive FC detected in | SH-SY5Y cells |
For other applications, we recommend the unconjugated version of this antibody, 60067-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Flow Cytometry (FC) | FC : 0.40 ug per 10^6 cells in a 100 µl suspension |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-60067 targets Neuropilin 1 in FC (Intra) applications and shows reactivity with human, pig samples.
| Tested Applications | FC (Intra) |
| Tested Reactivity | human, pig |
| Immunogen | Neuropilin 1 fusion protein Ag0931 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | neuropilin 1 |
| Synonyms | BDCA4, CD304, DKFZp686A03134, DKFZp781F1414, neuropilin 1, NRP, NRP1, VEGF165R |
| Calculated Molecular Weight | 103 kDa |
| Observed Molecular Weight | 130 kDa |
| GenBank Accession Number | BC007737 |
| Gene Symbol | NRP1 |
| Gene ID (NCBI) | 8829 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | O14786 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Neuropilin-1 (NRP1) is a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CL594 Neuropilin 1 antibody CL594-60067 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
