• Featured Product
  • KD/KO验证

Neuropilin 1 Monoclonal antibody

Neuropilin 1 Monoclonal Antibody for WB, IF/ICC, ELISA
Cat No. 60067-1-Ig

产品说明书

CloneNo. 2H3F6

宿主/亚型

Mouse / IgG1

种属反应性

human, pig, rabbit and More (2)

应用

WB, IF/ICC, ELISA and More (3)

NRP1, Neuropilin-1, CD304, BDCA4, 2H3F6

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inhuman placenta tissue, fetal human brain tissue, human plasma, 37°C incubated human placenta tissue, pig brain tissue, HeLa cells, rabbit heart tissue, MDA-MB-231 cells, A549 cells, pig heart tissue
Positive IF/ICC detected inSH-SY5Y cells, human embronic stem cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:6000
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

60067-1-Ig targets Neuropilin 1 in WB, IF/ICC, IP, CoIP, ELISA applications and shows reactivity with human, pig, rabbit samples.

经测试应用 WB, IF/ICC, ELISA Application Description
文献引用应用WB, IF, IP, CoIP
经测试反应性 human, pig, rabbit
文献引用反应性human, mouse, rabbit, xenopus
免疫原 Neuropilin 1 fusion protein Ag0931 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 neuropilin 1
别名 NRP1, Neuropilin-1, CD304, BDCA4, 2H3F6
计算分子量 103 kDa
观测分子量 130 kDa
GenBank蛋白编号BC007737
基因名称 Neuropilin 1
Gene ID (NCBI) 8829
RRIDAB_2150840
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO14786
储存缓冲液 PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Neuropilin-1 (NRP1) is a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.

实验方案

Product Specific Protocols
WB protocol for Neuropilin 1 antibody 60067-1-IgDownload protocol
IF protocol for Neuropilin 1 antibody 60067-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
XenopusIF

Elife

Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons.

Authors - Max Koppers
humanIF

Acta Biomater

Semaphorin-3A, Neuropilin-1 and Plexin-A1 in Prosthetic-Particle Induced Bone Loss.

Authors - S Saad
human

J Pathol

Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma.

Authors - Eric Morin
humanIF

Am J Cancer Res

CMTM6 promotes cell proliferation and invasion in oral squamous cell carcinoma by interacting with NRP1.

Authors - Yang Zheng
mouseWB

Pharm Res

Dual Receptor Targeting Cell Penetrating Peptide Modified Liposome for Glioma and Breast Cancer Postoperative Recurrence Therapy.

Authors - Yue Qiu
mouseIF

Exp Eye Res

Expression of axon guidance ligands and their receptors in the cornea and trigeminal ganglia and their recovery after corneal epithelium injury.

Authors - Victor H Guaiquil
Loading...