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验证数据展示

  • WB analysis of MCF-7 using 67336-1-Ig (same clone as 67336-1-PBS)

    WB analysis of MCF-7 using 67336-1-Ig (same clone as 67336-1-PBS)

    WB result of ODC1 antibody (67336-1-Ig; 1:30000; incubated at room temperature for 1.5 hours) with sh-Control and sh-ODC1 transfected MCF-7 cells. This data was developed using the same antibody clone with 67336-1-PBS in a different storage buffer formulation.

  • WB analysis of MCF-7 using 67336-1-Ig (same clone as 67336-1-PBS)

    WB analysis of MCF-7 using 67336-1-Ig (same clone as 67336-1-PBS)

    MCF-7 cells were subjected to SDS PAGE followed by western blot with 67336-1-Ig (ODC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67336-1-PBS in a different storage buffer formulation.

  • IF Staining of MCF-7 using 67336-1-Ig (same clone as 67336-1-PBS)

    IF Staining of MCF-7 using 67336-1-Ig (same clone as 67336-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using ODC1 antibody (67336-1-Ig, Clone: 2A1E3 ) at dilution of 1:1000 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 67336-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

ODC1 Monoclonal antibody, PBS Only

ODC1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 67336-1-PBS

产品说明书

CloneNo. 2A1E3

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

别名

ODC, EC:4.1.1.17, 2A1E3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67336-1-PBS targets ODC1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 ODC1 fusion protein Ag10927 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 ornithine decarboxylase 1
别名 ODC, EC:4.1.1.17, 2A1E3
计算分子量 461 aa, 51 kDa
观测分子量 51 kDa
GenBank蛋白编号BC025296
基因名称 ODC1
Gene ID (NCBI) 4953
RRIDAB_2882594
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP11926
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Ornithine decarboxylase (ODC) is also named as ODC1 and belongs to the Orn/Lys/Arg decarboxylase class-II family. It catalyzes the conversion of ornithine to putrescine, the first step and a major site of regulation of polyamine biosynthesis. The level of ODC is known to be controlled at several sites, namely transcription, translation, and enzyme degradation. Polyamines can stimulate the degradation of ODC as a type of negative feedback control (PMID:8486633). This protein can be phosphorylated in vivo (PMID:8798774). ODC1 can form a homodimer and only the dimer is catalytically active, as the active sites are constructed of residues from both monomers (PMID: 10623504). The molecular mass of ODC1 is 51 kDa, and the homodimer is 106 kDa.