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验证数据展示

  • WB analysis of human brain using 66513-1-Ig (same clone as 66513-1-PBS)

    WB analysis of human brain using 66513-1-Ig (same clone as 66513-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 66513-1-Ig (OLIG2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66513-1-PBS in a different storage buffer formulation.

OLIG2 Monoclonal antibody, PBS Only

OLIG2 Monoclonal Antibody for WB, ELISA
Cat No. 66513-1-PBS

产品说明书

CloneNo. 1E8C5

宿主/亚型

Mouse / IgG2a

种属反应性

Human, mouse, rat

应用

WB, ELISA

别名

BHLHB1, bHLHe19, OLIG2, OLIGO2, PRKCBP2, RACK17

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy OLIG2 Ready-To-Use IHC Kit. OLIG2 primary antibody included.

产品信息

66513-1-PBS targets OLIG2 in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 Human, mouse, rat
免疫原 OLIG2 fusion protein Ag18838 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 oligodendrocyte lineage transcription factor 2
别名 BHLHB1, bHLHe19, OLIG2, OLIGO2, PRKCBP2, RACK17
计算分子量 32 kDa
观测分子量 35-39 kDa
GenBank蛋白编号BC047511
基因名称 OLIG2
Gene ID (NCBI) 10215
RRIDAB_2881876
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ13516
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

OLIG2, also named as BHLHB1, BHLHE19, PRKCBP2 and RACK17, is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1, OLIG2 establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. OLIG2 is widely expressed in subsets of glia cells and progenitors, and it is strongly induced at different sites by both acute and chronic injury, albeit with different mechanisms. OLIG2 acts as a repressor of neurogenesis in cells reacting to brain injury. It may represent an effective approach towards evoking neuronal repair from parenchymal precursors.(PMID:19390819 )