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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84295-3-RR (same clone as 84295-3-PBS)

    WB analysis using 84295-3-RR (same clone as 84295-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84295-3-RR (P glycoprotein antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84295-3-PBS in a different storage buffer formulation.

P glycoprotein Recombinant antibody, PBS Only

P glycoprotein Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84295-3-PBS

产品说明书

CloneNo. 241512A1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

ABCB1, 241512A1, EC:7.6.2.2, EC:7.6.2.1, ATP-dependent translocase ABCB1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy ABCB1 Ready-To-Use IHC Kit. ABCB1 primary antibody included.

产品信息

84295-3-PBS targets P glycoprotein in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 ATP-binding cassette, sub-family B (MDR/TAP), member 1
别名 ABCB1, 241512A1, EC:7.6.2.2, EC:7.6.2.1, ATP-dependent translocase ABCB1
计算分子量 1280 aa, 142 kDa
观测分子量 130-150 kDa
GenBank蛋白编号BC130424
基因名称 P glycoprotein
Gene ID (NCBI) 5243
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP08183
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.