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P glycoprotein Recombinant antibody, PBS Only

P glycoprotein Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241512A1

Cat no : 84295-3-PBS

Print datasheet

Synonyms

ABCB1, 241512A1, EC:7.6.2.2, EC:7.6.2.1, ATP-dependent translocase ABCB1

验证数据展示

  • WB analysis using 84295-3-RR (same clone as 84295-3-PBS)

    WB analysis using 84295-3-RR (same clone as 84295-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84295-3-RR (P glycoprotein antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84295-3-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy ABCB1 Ready-To-Use IHC Kit. ABCB1 primary antibody included.

产品信息

84295-3-PBS targets P glycoprotein in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name ATP-binding cassette, sub-family B (MDR/TAP), member 1
Synonyms ABCB1, 241512A1, EC:7.6.2.2, EC:7.6.2.1, ATP-dependent translocase ABCB1
Calculated Molecular Weight 1280 aa, 142 kDa
Observed Molecular Weight 130-150 kDa
GenBank Accession NumberBC130424
Gene Symbol P glycoprotein
Gene ID (NCBI) 5243
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP08183
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.