验证数据展示
产品信息
68317-1-PBS targets PBLD in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, pig samples.
Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | Human, pig |
Immunogen | PBLD fusion protein Ag23827 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | phenazine biosynthesis-like protein domain containing |
Synonyms | FLJ14767, FLJ35507, MAWBP, MAWD binding protein, MAWDBP, PBLD |
Observed Molecular Weight | 30 kDa |
GenBank Accession Number | BC009738 |
Gene Symbol | PBLD |
Gene ID (NCBI) | 64081 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P30039 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PBLD, also termed as MAWBP, was first identified from a human liver cDNA library using a yeast two-hybrid technique by Iriyama et al. As the only representative of phenazine biosynthesis-like protein family, PBLD is widely expressed in human tissues, such as brain, heart, lung, liver, pancreas, kidney, and placenta. Its expression is elevated in several diseases processes, including insulin resistance, folate deficiency, and hypotension. PBLD has been proved to be involved in gastric carcinogenesis, PBLD expression was attenuated in gastric cancer (GC) tissues, and negatively regulated the growth and invasion in gastric cancer cell-lines by inhibiting TGF-β1-induced EMT (Epithelial-Mesenchymal Transition).(PMID: 11355021, 17929853, 23687415, 26594798)