验证数据展示
产品信息
67832-1-PBS targets PDE6A in WB, ELISA applications and shows reactivity with Human, Mouse, Rat samples.
Tested Applications | WB, ELISA Application Description |
Tested Reactivity | Human, Mouse, Rat |
Immunogen | PDE6A fusion protein Ag16741 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | phosphodiesterase 6A, cGMP-specific, rod, alpha |
Synonyms | CGPR A, GMP PDE alpha, PDE V B1, PDE6 alpha, PDE6A, PDEA |
Calculated Molecular Weight | 860 aa, 100 kDa |
Observed Molecular Weight | 100 kDa |
GenBank Accession Number | BC035909 |
Gene Symbol | PDE6A |
Gene ID (NCBI) | 5145 |
RRID | AB_2918594 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P16499 |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PDE6A(Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) is also named as GMP-PDE alpha, PDE V-B1, PDEA and belongs to the cyclic nucleotide phosphodiesterase family. PDE6A contains an open reading frame capable of coding for a polypeptide of 859 amino acids and about 100 kDa. It is a subunit of a key phototransduction enzyme which participates in processes of transmission and amplification of the visual signal. The expression of PDE6 alpha in retina is essential for normal expression of PDE6 beta and PDE6 gama.