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PEA15 Recombinant antibody, PBS Only

PEA15 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241044H6

Cat no : 83958-3-PBS

Print datasheet

Synonyms

MAT1H, MAT1, HUMMAT1H, HMAT1, Astrocytic phosphoprotein PEA-15

验证数据展示

  • IF Staining of A431 using 83958-3-RR (same clone as 83958-3-PBS)

    IF Staining of A431 using 83958-3-RR (same clone as 83958-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using PEA15 antibody (83958-3-RR, Clone: 241044H6 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83958-3-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 83958-3-RR (same clone as 83958-3-PBS)

    IF Staining of A431 using 83958-3-RR (same clone as 83958-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using PEA15 antibody (83958-3-RR, Clone: 241044H6 ) at dilution of 1:500 and CoraLite®594-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-4). This data was developed using the same antibody clone with 83958-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83958-3-RR

    Affinity and Kinetic Characterization of 83958-3-RR

    Biolayer interferometry (BLl) kinetic assays of 83958-3-RR against Human PEA15 were performed. The affinity constant is 6.95 nM.

产品信息

83958-3-PBS targets PEA15 in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen PEA15 fusion protein Ag13782 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name phosphoprotein enriched in astrocytes 15
Synonyms MAT1H, MAT1, HUMMAT1H, HMAT1, Astrocytic phosphoprotein PEA-15
Calculated Molecular Weight 130 aa, 15 kDa
Observed Molecular Weight 15 kDa
GenBank Accession NumberBC002426
Gene Symbol PEA15
Gene ID (NCBI) 8682
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ15121
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Phosphoprotein Enriched in Astrocytes 15 kDa (PEA15), also known as PED-15, is a small, death effector-domain (DED)-containing protein that was recently demonstrated to inhibit tumor necrosis factor-α-induced apoptosis and to reverse the inhibition of integrin activation due to H-Ras. PEA15 is a 15 kDa protein that is highly expressed in the nervous system with particularly high levels in astrocytes and neurons of the hippocampus. PEA15 is a cytoplasmic protein that sits at an important junction in intracellular signalling and can regulate diverse cellular processes, such as proliferation and apoptosis, dependent upon stimulation.