• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

PERM1 Recombinant antibody, PBS Only

PERM1 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241613B6

Cat no : 84425-5-PBS

Print datasheet

Synonyms

PERM, C1orf170, 241613B6

验证数据展示

  • IF Staining of H9C2 using 84425-5-RR (same clone as 84425-5-PBS)

    IF Staining of H9C2 using 84425-5-RR (same clone as 84425-5-PBS)

    Immunofluorescent analysis of (4% PFA) fixed H9C2 cells using PERM1 antibody (84425-5-RR, Clone: 241613B6 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84425-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84425-5-RR

    Affinity and Kinetic Characterization of 84425-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84425-5-RR against Human PERM1 were performed. The affinity constant is below 1 pM.

产品信息

84425-5-PBS targets PERM1 in IF/ICC, Indirect ELISA applications and shows reactivity with human, rat samples.

Tested Applications IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, rat
Immunogen PERM1 fusion protein Ag23833 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name chromosome 1 open reading frame 170
Synonyms PERM, C1orf170, 241613B6
GenBank Accession NumberBC006300
Gene Symbol C1orf170
Gene ID (NCBI) 84808
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ5SV97
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PERM1 (PGC-1/ERR-induced regulator in muscle 1) is a muscle-specific protein induced by PGC-1α and ERRα. PERM1 protein expression is mainly restricted to heart and skeletal muscle, indicating PERM1 functions as a tissue-specific regulator of mitochondrial biogenesis in response to exercise (PMID: 33549681, 36028747). Ablation of Perm1 in mice results in reduced protein expression of lipin-1 accompanied by accumulation of specific phospholipid species (PMID: 33549681). There are two major isoforms of Perm1 protein, the short isoform is about 85 kDa, and the long isoform is 105 kDa.