验证数据展示
产品信息
68240-1-PBS targets PSMA2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, pig, rat samples.
Tested Applications | WB, IHC, Indirect ELISA Application Description |
Tested Reactivity | Human, mouse, pig, rat |
Immunogen | PSMA2 fusion protein Ag5837 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | proteasome (prosome, macropain) subunit, alpha type, 2 |
Synonyms | HC3, Macropain subunit C3, MU, PMSA2, Proteasome component C3, PSC2, PSC3, PSMA2 |
Calculated Molecular Weight | 26 kDa |
Observed Molecular Weight | 26 kDa |
GenBank Accession Number | BC047697 |
Gene Symbol | PSMA2 |
Gene ID (NCBI) | 5683 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P25787 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PSMA2 (Proteasome subunit alpha type-2) is the essential subunit that contributes to the complete assembly of 20S proteasome complex, involved in the proteolytic degradation of most intracellular proteins. It is required in spermatogenesis and generation of a subset of MHC class I-presented antigenic peptides(PMID: 34711951, PMID: 27342858). Dysregulation of PSMA2 degradation leads to tumorigenesis including cervical cancer (PMID:33684886).