PTEN Monoclonal antibody

PTEN Monoclonal Antibody for WB, ELISA
Cat No. 60300-3-Ig

产品说明书

CloneNo. 4D8G9

宿主/亚型

Mouse / IgG2b

种属反应性

human, mouse

应用

WB, ELISA and More (1)

10q23del, 4D8G9, Bannayan Zonana syndrome, BC005821, BZS

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells, MCF-7 cells, DU 145 cells, HT-29 cells, NIH/3T3 cells
Planning an IHC experiment? We recommend our IHCeasy PTEN Ready-To-Use IHC Kit. PTEN primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

60300-3-Ig targets PTEN in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB, IHC
经测试反应性 human, mouse
文献引用反应性human
免疫原 PTEN fusion protein Ag17274 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 phosphatase and tensin homolog
别名 10q23del, 4D8G9, Bannayan Zonana syndrome, BC005821, BZS
计算分子量 47 kDa
观测分子量 55 kDa
GenBank蛋白编号BC005821
基因名称 PTEN
Gene ID (NCBI) 5728
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP60484
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PTEN (also designated MMAC1), products of tumor suppressor genes, are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors, such as brain, breast, kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa.

实验方案

Product Specific Protocols
WB protocol for PTEN antibody 60300-3-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

J Immunother

Taurine Inhibits Lung Metastasis in Triple-Negative Breast Cancer by Modulating Macrophage Polarization Through PTEN-PI3K/Akt/mTOR Pathway

Authors - Yufeng Lin
humanIHC

Cell Death Discov

Myeloid PTEN loss affects the therapeutic response by promoting stress granule assembly and impairing phagocytosis by macrophages in breast cancer

Authors - Yan Li
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