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PTPIP51 Monoclonal antibody, PBS Only

PTPIP51 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G11E2

Cat no : 68582-1-PBS

Print datasheet

Synonyms

FAM82A2, 1G11E2, hucep-10, hRMD-3, hRMD 3

验证数据展示

  • IF Staining of HeLa using 68582-1-Ig (same clone as 68582-1-PBS)

    IF Staining of HeLa using 68582-1-Ig (same clone as 68582-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using PTPIP51 antibody (68582-1-Ig, Clone: 1G11E2 ) at dilution of 1:476 and Multi-rAb CoraLite® Plus 594-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (Cat.NO. RGAM004 ). This data was developed using the same antibody clone with 68582-1-PBS in a different storage buffer formulation.

  • WB analysis using 68582-1-Ig (same clone as 68582-1-PBS)

    WB analysis using 68582-1-Ig (same clone as 68582-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68582-1-Ig (PTPIP51 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68582-1-PBS in a different storage buffer formulation.

产品信息

68582-1-PBS targets PTPIP51 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen PTPIP51 fusion protein Ag15135 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name family with sequence similarity 82, member A2
Synonyms FAM82A2, 1G11E2, hucep-10, hRMD-3, hRMD 3
Calculated Molecular Weight 470 aa, 52 kDa
Observed Molecular Weight52-60 kDa
GenBank Accession NumberBC008970
Gene Symbol PTPIP51
Gene ID (NCBI) 55177
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ96TC7
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Protein tyrosine phosphatase-interacting protein 51 (PTPIP51),also known as RMDN3, is a mitochondrial membrane-anchored protein that interacts with ER membrane-bound VAPB. The VAPB-PTPIP51 interaction impacts on intracellular Ca2+ handling (PMID: 22131369, 28345618). PTPIP51 participates in multiple cellular processes, and dysfunction of PTPIP51 is implicated in diseases such as cancer and neurodegenerative disorders (PMID: 28345618).The known initiation sites in the Ptpip51 gene would lead to molecular protein masses of 52, 38 and 30 kDa (PMID: 18854601,19844996).