CoraLite® Plus 488-conjugated Podocalyxin Monoclonal antibody

Podocalyxin Monoclonal Antibody for
Cat No. CL488-68250

产品说明书

CloneNo. 4A3C7

宿主/亚型

Mouse / IgG2a

种属反应性

Human

应用

GCTM 2 antigen, Gp200, PC, PCLP, PCLP 1, PCLP1, Podocalyxin, podocalyxin like, Podocalyxin like protein 1, PODXL, RCC marker, TRA 1 81,TRA 1 60

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy Podocalyxin Ready-To-Use IHC Kit. Podocalyxin primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 68250-1-Ig

产品信息

CL488-68250 targets Podocalyxin in applications and shows reactivity with Human samples.

经测试应用 Application Description
经测试反应性 Human
免疫原 Podocalyxin fusion protein Ag12859 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 podocalyxin-like
别名 GCTM 2 antigen, Gp200, PC, PCLP, PCLP 1, PCLP1, Podocalyxin, podocalyxin like, Podocalyxin like protein 1, PODXL, RCC marker, TRA 1 81,TRA 1 60
计算分子量 526 aa, 55 kDa
观测分子量60-70 kDa
GenBank蛋白编号BC093730
基因名称 Podocalyxin
Gene ID (NCBI) 5420
RRIDAB_3084456
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO00592
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Podocalyxin, also known as podocalyxin-like protein 1 (PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus, but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers. Podocalyxin is a protein with a peptide bone of ∼55.5 kDa that undergoes a post‐translational glycosylation, the different molecular mass of podocalyxin indicates the extent and variability of glycosylation patterns (PMID: 17092254).

实验方案

Product Specific Protocols
FC protocol for CL Plus 488 Podocalyxin antibody CL488-68250Download protocol
Standard Protocols
Click here to view our Standard Protocols
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