验证数据展示
产品信息
67335-1-PBS targets RCC1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse samples.
Tested Applications | WB, IHC, Indirect ELISA Application Description |
Tested Reactivity | Human, mouse |
Immunogen | RCC1 fusion protein Ag17809 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | regulator of chromosome condensation 1 |
Synonyms | Cell cycle regulatory protein, CHC1, RCC1, RCC1 I |
Calculated Molecular Weight | 421 aa, 45 kDa |
Observed Molecular Weight | 45-50 kDa |
GenBank Accession Number | BC010067 |
Gene Symbol | RCC1 |
Gene ID (NCBI) | 1104 |
RRID | AB_2882593 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P18754 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation.