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验证数据展示

  • IF Staining of Jurkat using CL488-67143

    IF Staining of Jurkat using CL488-67143

    Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using CoraLite® Plus 488 RIAM,APBB1IP antibody (CL488-67143, Clone: 2F8A2 ) at dilution of 1:200.

CoraLite® Plus 488-conjugated RIAM,APBB1IP Monoclonal antibody

RIAM,APBB1IP Monoclonal Antibody for IF/ICC
Cat No. CL488-67143

产品说明书

CloneNo. 2F8A2

宿主/亚型

Mouse / IgG2a

种属反应性

Human, Mouse

应用

IF/ICC

别名

APBB1 interacting protein 1, APBB1IP, APBB1IP,RIAM, INAG1, PREL 1, PREL1, Proline rich EVH1 ligand 1, Proline rich protein 73, RARP 1, RARP1, RIAM, RIAM,APBB1IP

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

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经过测试的应用

Positive IF/ICC detected inJurkat cells
For other applications, we recommend the unconjugated version of this antibody, 67143-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-67143 targets RIAM,APBB1IP in IF/ICC applications and shows reactivity with Human, Mouse samples.

经测试应用 IF/ICC Application Description
经测试反应性 Human, Mouse
免疫原 RIAM,APBB1IP fusion protein Ag4602 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
别名 APBB1 interacting protein 1, APBB1IP, APBB1IP,RIAM, INAG1, PREL 1, PREL1, Proline rich EVH1 ligand 1, Proline rich protein 73, RARP 1, RARP1, RIAM, RIAM,APBB1IP
计算分子量 666 aa, 73 kDa
观测分子量 100 kDa
GenBank蛋白编号BC035636
基因名称 RIAM
Gene ID (NCBI) 54518
RRIDAB_3084315
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ7Z5R6
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

APBB1IP gene encodes a Rap1-GTP-interacting adapter molecule (RIAM) which is an important protein in Rap1-mediated integrin activation and adhesion. Rap1 is a small GTPase frequently activated in tumors such as melanoma and prostate cancer. RIAM is widely expressed with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes. RIAM may function in the signal transduction from Ras activation to actin cytoskeletal remodeling. The observed molecular weight of RIAM is about 100 kDa.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 RIAM,APBB1IP antibody CL488-67143Download protocol
Standard Protocols
Click here to view our Standard Protocols