验证数据展示
经过测试的应用
Positive IF-P detected in | human tonsillitis tissue |
推荐稀释比
应用 | 推荐稀释比 |
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Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL594-67143 targets RIAM,APBB1IP in IF-P applications and shows reactivity with Human, Mouse samples.
经测试应用 | IF-P Application Description |
经测试反应性 | Human, Mouse |
免疫原 | RIAM,APBB1IP fusion protein Ag4602 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
别名 | APBB1 interacting protein 1, APBB1IP, APBB1IP,RIAM, INAG1, PREL 1, PREL1, Proline rich EVH1 ligand 1, Proline rich protein 73, RARP 1, RARP1, RIAM, RIAM,APBB1IP |
计算分子量 | 666 aa, 73 kDa |
观测分子量 | 100 kDa |
GenBank蛋白编号 | BC035636 |
基因名称 | RIAM |
Gene ID (NCBI) | 54518 |
RRID | AB_3084751 |
偶联类型 | CoraLite®594 Fluorescent Dye |
最大激发/发射波长 | 588 nm / 604 nm |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q7Z5R6 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
APBB1IP gene encodes a Rap1-GTP-interacting adapter molecule (RIAM) which is an important protein in Rap1-mediated integrin activation and adhesion. Rap1 is a small GTPase frequently activated in tumors such as melanoma and prostate cancer. RIAM is widely expressed with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes. RIAM may function in the signal transduction from Ras activation to actin cytoskeletal remodeling. The observed molecular weight of RIAM is about 100 kDa.
实验方案
Product Specific Protocols | |
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IF protocol for CL594 RIAM,APBB1IP antibody CL594-67143 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |