验证数据展示
产品信息
21028-1-PBS targets RNF213 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, IP, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | RNF213 fusion protein Ag15335 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | ring finger protein 213 |
别名 | ring finger protein 213, Protein ALO17, KIAA1618, KIAA1554, C17orf27 |
计算分子量 | 3280 aa, 374 kDa |
GenBank蛋白编号 | BC032220 |
基因名称 | RNF213 |
Gene ID (NCBI) | 57674 |
RRID | AB_2878793 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen Affinity purified |
UNIPROT ID | Q63HN8 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RNF213 is a typical E3 ubiquitin ligase that can catalyze ubiquitination of both proteins and lipids, and which is involved in various processes, such as lipid metabolism, angiogenesis and cell-autonomous immunity (PMID: 21799892, 26126547, 26278786, 26766444, 30705059).RNF213 contains a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions.