验证数据展示
产品信息
67999-1-PBS targets RPA2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat, pig, rabbit |
Immunogen | RPA2 fusion protein Ag24783 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | replication protein A2, 32kDa |
Synonyms | RP A p32, RF-A protein 2, replication protein A2, 32kDa, Replication factor A protein 2, REPA2 |
Calculated Molecular Weight | 29 kDa |
Observed Molecular Weight | 30 kDa |
GenBank Accession Number | BC001630 |
Gene Symbol | RPA2 |
Gene ID (NCBI) | 6118 |
RRID | AB_2918747 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P15927 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RPA2, a subunit of the heterotrimeric replication protein A (RPA) complex, is overexpressed in various cancers. RPA2 is a major target for upstream kinases, including CDKs and the three PIKKs (ATR, ataxia-telangiectasia mutated [ATM], and DNA-PK). RPA2 comprises multiple critical Ser/Thr residues that are phosphorylated in sequential order in response to genotoxic stress.