验证数据展示
产品信息
84670-3-PBS targets RPL11 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | RPL11 fusion protein Ag9356 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | ribosomal protein L11 |
别名 | GIG34, DBA7, CLL-associated antigen KW-12, CLL associated antigen KW 12, 60S ribosomal protein L11 |
计算分子量 | 177 aa, 20 kDa |
观测分子量 | 20 kDa |
GenBank蛋白编号 | BC018970 |
基因名称 | RPL11 |
Gene ID (NCBI) | 6135 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | P62913 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Ribosomal protein L11 is one of 80 mammalian ribosome proteins. It can bind to 5S ribosomal RNA, for it's required for rRNA maturation and formation of the 60S ribosomal subunit. It can inhibit 40S or 60S ribosome biogenesis via mediated p53 induction. Once retained by PICT1 in the nucleolus, RPL11 involve in regulation of the MDM2-P53 pathway and promotion of tumor progression.