验证数据展示
产品信息
66480-1-PBS targets RhoGDI in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, Mouse, Rat |
免疫原 | RhoGDI fusion protein Ag0791 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | Rho GDP dissociation inhibitor (GDI) alpha |
别名 | aGDI, ARHGDIA, GDIA1, Rho GDI 1, Rho GDI alpha, RHOGDI, RHOGDI 1 |
计算分子量 | 28 kDa |
观测分子量 | 28 kDa |
GenBank蛋白编号 | BC005851 |
基因名称 | RhoGDI |
Gene ID (NCBI) | 396 |
RRID | AB_2881846 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P52565 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Rho GDP-dissociation inhibitor (RhoGDI), also called ARHGDIA, is one member of ARHGDIs, which is ubiquitously expressed and interacts with several Rho GTPases, mainly including RhoA, Rac1, and Cdc42. RhoGDI can inhibit nucleotide exchange and membrane association to downregulate the activities of Rho family GTPase. It is overexpressed in various human cancers. Activity of this protein is important in a variety of cellular processes, and it is overexpressed in various human cancers. Mutations in RhoGDI have been found in individuals with nephrotic syndrome, type 8.