- Featured Product
- KD/KO Validated
CoraLite®594-conjugated SDCCAG8 Polyclonal antibody
SDCCAG8 Polyclonal Antibody for IF/ICC
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat, zebrafish, Canine
Applications
IF/ICC
Conjugate
CoraLite®594 Fluorescent Dye
验证数据展示
经过测试的应用
| Positive IF/ICC detected in | MDCK cells |
For other applications, we recommend the unconjugated version of this antibody, 13471-1-AP
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-13471 targets SDCCAG8 in IF/ICC applications and shows reactivity with human, mouse, rat, zebrafish, Canine samples.
| Tested Applications | IF/ICC Application Description |
| Tested Reactivity | human, mouse, rat, zebrafish, Canine |
| Immunogen | SDCCAG8 fusion protein Ag4264 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | serologically defined colon cancer antigen 8 |
| Synonyms | Antigen NY CO 8, BBS16, CCCAP, hCCCAP, HSPC085, NY CO 8, SDCCAG8 |
| Calculated Molecular Weight | 713 aa, 83 kDa |
| GenBank Accession Number | BC032454 |
| Gene Symbol | SDCCAG8 |
| Gene ID (NCBI) | 10806 |
| RRID | AB_2919796 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q86SQ7 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SDCCAG8, also named as CCCAP and NY-CO-8, plays a role in the establishment of cell polarity and epithelial lumen formation. It may play a role in ciliogenesis. Loss of SDCCAG8 function as a cause of a retinal-renal ciliopathy and validates exome capture analysis for broadly heterogeneous single-gene disorders. SDCCAG8 is localized at both centrioles and interacts directly with OFD1 (oral-facial-digital syndrome 1), which is associated with NPHP-RC. SDCCAG8 has 4 isoforms with MW 83,78,73 and 41 kDa (refer to UniProt). Catalog#13471-1-AP can recognize all the four isoforms.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 SDCCAG8 antibody CL594-13471 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |