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验证数据展示

  • IF Staining of human liver cancer using CL488-67792

    IF Staining of human liver cancer using CL488-67792

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite® Plus 488 SERBP1 antibody (CL488-67792, Clone: 1D4H1 ) at dilution of 1:200. DAPI (blue)

CoraLite® Plus 488-conjugated SERBP1 Monoclonal antibody

SERBP1 Monoclonal Antibody for IF-P
Cat No. CL488-67792

Print datasheet

CloneNo. 1D4H1

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat

Applications

IF-P

Synonyms

CGI 55, CHD3IP, DKFZp564M2423, FLJ90489, HABP4L, PAI RBP1, PAI1 RNA binding protein 1, PAIRBP1, SERBP1

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  CoraLite® Plus 488

Size: 
100 μL

¥2800/ 100 μL

浓度: 1000 μg/ml

库存：1-2周货期

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经过测试的应用

Positive IF-P detected inhuman liver cancer tissue
For other applications, we recommend the unconjugated version of this antibody, 67792-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-67792 targets SERBP1 in IF-P applications and shows reactivity with Human, Mouse, Rat samples.

Tested Applications IF-P Application Description
Tested Reactivity Human, Mouse, Rat
Immunogen SERBP1 fusion protein Ag30202 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name SERPINE1 mRNA binding protein 1
Synonyms CGI 55, CHD3IP, DKFZp564M2423, FLJ90489, HABP4L, PAI RBP1, PAI1 RNA binding protein 1, PAIRBP1, SERBP1
Calculated Molecular Weight 45 kDa
Observed Molecular Weight50 kDa
GenBank Accession NumberBC008045
Gene Symbol SERBP1
Gene ID (NCBI) 26135
RRIDAB_2919549
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ8NC51
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The plasminogen activator system (PA) plays an important role in invasion and metastasis of solid tumors. The PA Inhibitor type 1 (PAI-1) is the main physiologic regulator of plasminogen activation. PAI-RBP1 (PAI-1 mRNA Binding Protein 1, also named SERBP1), is an RNA-binding protein containing an RG-rich domain and an RGG box domain that might be methylated by protein arginine N-methyltransferases (PRMTs). SERBP1 was identified as an interacting partner of a Tudor domain containing protein TDRD3, and can localize to cytoplasmic stress granules (SGs).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 SERBP1 antibody CL488-67792Download protocol
Standard Protocols
Click here to view our Standard Protocols