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验证数据展示

  • IF Staining of human liver cancer using CL488-67792

    IF Staining of human liver cancer using CL488-67792

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite® Plus 488 SERBP1 antibody (CL488-67792, Clone: 1D4H1 ) at dilution of 1:200. DAPI (blue)

CoraLite® Plus 488-conjugated SERBP1 Monoclonal antibody

SERBP1 Monoclonal Antibody for IF-P
Cat No. CL488-67792

产品说明书

CloneNo. 1D4H1

宿主/亚型

Mouse / IgG1

种属反应性

Human, Mouse, Rat

应用

IF-P

别名

CGI 55, CHD3IP, DKFZp564M2423, FLJ90489, HABP4L, PAI RBP1, PAI1 RNA binding protein 1, PAIRBP1, SERBP1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

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经过测试的应用

Positive IF-P detected inhuman liver cancer tissue
For other applications, we recommend the unconjugated version of this antibody, 67792-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-67792 targets SERBP1 in IF-P applications and shows reactivity with Human, Mouse, Rat samples.

经测试应用 IF-P Application Description
经测试反应性 Human, Mouse, Rat
免疫原 SERBP1 fusion protein Ag30202 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 SERPINE1 mRNA binding protein 1
别名 CGI 55, CHD3IP, DKFZp564M2423, FLJ90489, HABP4L, PAI RBP1, PAI1 RNA binding protein 1, PAIRBP1, SERBP1
计算分子量 45 kDa
观测分子量50 kDa
GenBank蛋白编号BC008045
基因名称 SERBP1
Gene ID (NCBI) 26135
RRIDAB_2919549
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ8NC51
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The plasminogen activator system (PA) plays an important role in invasion and metastasis of solid tumors. The PA Inhibitor type 1 (PAI-1) is the main physiologic regulator of plasminogen activation. PAI-RBP1 (PAI-1 mRNA Binding Protein 1, also named SERBP1), is an RNA-binding protein containing an RG-rich domain and an RGG box domain that might be methylated by protein arginine N-methyltransferases (PRMTs). SERBP1 was identified as an interacting partner of a Tudor domain containing protein TDRD3, and can localize to cytoplasmic stress granules (SGs).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 SERBP1 antibody CL488-67792Download protocol
Standard Protocols
Click here to view our Standard Protocols