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SLC25A1 Monoclonal antibody, PBS Only

SLC25A1 Monoclonal Antibody for WB,Indirect ELISA

Host / Isotype

Mouse / IgG3

Reactivity

Human, Mouse, Rat

Applications

WB,Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1F11A3

Cat No : 66771-1-PBS

Print datasheet

Synonyms

Citrate transport protein, CTP, SLC20A3, SLC25A1, Tricarboxylate carrier protein

验证数据展示

  • WB analysis using 66771-1-Ig (same clone as 66771-1-PBS)

    WB analysis using 66771-1-Ig (same clone as 66771-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66771-1-Ig (SLC25A1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 66771-1-PBS in a different storage buffer formulation.

  • WB analysis using 66771-1-Ig (same clone as 66771-1-PBS)

    WB analysis using 66771-1-Ig (same clone as 66771-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66771-1-Ig (SLC25A1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66771-1-PBS in a different storage buffer formulation.

产品信息

66771-1-PBS targets SLC25A1 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Applications WB,Indirect ELISA Application Description
Tested Reactivity Human, Mouse, Rat
Immunogen SLC25A1 fusion protein Ag7520 种属同源性预测
Host / Isotype Mouse / IgG3
Class Monoclonal
Type Antibody
Full Name solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
Synonyms Citrate transport protein, CTP, SLC20A3, SLC25A1, Tricarboxylate carrier protein
Calculated Molecular Weight 34 kDa
Observed Molecular Weight 34 kDa
GenBank Accession NumberBC004980
Gene Symbol SLC25A1
Gene ID (NCBI) 6576
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP53007
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

SLC25A1, also known as CIC or CTP, is a mitochondrial citrate transporter that exports citrate from the mitochondria to the cytosol. SLC25A1 is highly expressed in several tumor types. Recently it has been identified as a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. In addition, defects in SLC25A1 has been found as a cause of combined D-2- and L-2-hydroxyglutaric aciduria. This antibody specifically recognized the endogenous SLC25A1; no protein was detected in cells from subjects containing two alleles with truncating mutations with this antibody. (24681808, 23561848)