验证数据展示
产品信息
66771-1-PBS targets SLC25A1 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, Mouse, Rat |
免疫原 | SLC25A1 fusion protein Ag7520 种属同源性预测 |
宿主/亚型 | Mouse / IgG3 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 |
别名 | Citrate transport protein, CTP, SLC20A3, SLC25A1, Tricarboxylate carrier protein |
计算分子量 | 34 kDa |
观测分子量 | 34 kDa |
GenBank蛋白编号 | BC004980 |
基因名称 | SLC25A1 |
Gene ID (NCBI) | 6576 |
RRID | AB_2882117 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P53007 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SLC25A1, also known as CIC or CTP, is a mitochondrial citrate transporter that exports citrate from the mitochondria to the cytosol. SLC25A1 is highly expressed in several tumor types. Recently it has been identified as a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. In addition, defects in SLC25A1 has been found as a cause of combined D-2- and L-2-hydroxyglutaric aciduria. This antibody specifically recognized the endogenous SLC25A1; no protein was detected in cells from subjects containing two alleles with truncating mutations with this antibody. (24681808, 23561848)