PE-conjugated SNRNP200 Polyclonal antibody

SNRNP200 Polyclonal Antibody for FC (Intra)
Cat No. PE-23875

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

FC (Intra)

KIAA0788, HELIC2, EC:3.6.4.13, BRR2, ASCC3L1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  PE
规格: 

-/ -


经过测试的应用

Positive FC (Intra) detected inA431 cells
Planning an IHC experiment? We recommend our IHCeasy SNRNP200 Ready-To-Use IHC Kit. SNRNP200 primary antibody included.

推荐稀释比

应用推荐稀释比
Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.20 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

PE-23875 targets SNRNP200 in FC (Intra) applications and shows reactivity with human, mouse samples.

经测试应用 FC (Intra) Application Description
经测试反应性 human, mouse
免疫原 SNRNP200 fusion protein Ag20748 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 small nuclear ribonucleoprotein 200kDa (U5)
别名 KIAA0788, HELIC2, EC:3.6.4.13, BRR2, ASCC3L1
计算分子量 494 aa, 57 kDa
观测分子量 200-245 kDa
GenBank蛋白编号BC001417
基因名称 SNRNP200
Gene ID (NCBI) 23020
RRIDAB_3673989
偶联类型 PE Fluorescent Dye
最大激发/发射波长496 nm, 565 nm / 578 nm
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO75643
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

SNRNP200 (small nuclear ribonucleoprotein 200kDa (U5)), also known as HELIC2, ASCC3L1 or BRR2, is a 2,136 amino acid protein that localizes to the nucleus and contains two SEC63 domains, two helicase C-terminal domains and two helicase ATP-binding domains. Existing as multiple alternatively spliced isoforms, HELIC2 functions as an RNA helicase that is thought to promote specific RNA-RNA conformational changes which are important in the second step of RNA splicing. The gene encoding HELIC2 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, hich also map to chromosome 2. The observed molecular weight of SNRNP200 is 200-245kd.

实验方案

Product Specific Protocols
FC protocol for PE SNRNP200 antibody PE-23875Download protocol
Standard Protocols
Click here to view our Standard Protocols
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