CoraLite® Plus 488-conjugated SNX18 Monoclonal antibody
SNX18 Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
Human, Mouse
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2E7D6
验证数据展示
经过测试的应用
Positive IF/ICC detected in | A431 cells |
For other applications, we recommend the unconjugated version of this antibody, 68305-1-Ig
推荐稀释比
Application | Dilution |
---|---|
Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-68305 targets SNX18 in IF/ICC applications and shows reactivity with Human, Mouse samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | Human, Mouse |
Immunogen | SNX18 fusion protein Ag17388 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | sorting nexin 18 |
Synonyms | FLJ11997, FLJ32560, FLJ61062, SH3PX2, SH3PXD3B, SNAG1, SNX18, sorting nexin 18 |
Calculated Molecular Weight | 628 aa, 69 kDa |
Observed Molecular Weight | 67-70 kDa |
GenBank Accession Number | BC060791 |
Gene Symbol | SNX18 |
Gene ID (NCBI) | 112574 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q96RF0 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SNXs (sorting nexins) are a diverse group of cytoplasmic and membrane-associated proteins that are classified by the presence of a phospholipid-binding motif-the PX domain (PMID:12461558). SNXs are involved in endocytosis and protein trafficking. SNX18, together with SNX9 and SNX33, constitutes a separate SNX9 subfamily which is required for mitosis through endocytosis processes (PMID: 22718350, 20427313). SNX18 acts as a positive regulator of autophagy, regulates ATG9A trafficking from recycling endosomes (PMID: 24113029, 29437695).
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 SNX18 antibody CL488-68305 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |