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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated SOD2 Monoclonal antibody

SOD2 Monoclonal Antibody for

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat, pig

Applications

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

3A6C2

Cat no : CL488-66474

Print datasheet

Synonyms

SODM, MNSOD, Mn SOD, IPOB, IPO B

验证数据展示

Planning an IHC experiment? We recommend our IHCeasy SOD2 Ready-To-Use IHC Kit. SOD2 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66474-1-Ig

产品信息

CL488-66474 targets SOD2 in applications and shows reactivity with human, mouse, rat, pig samples.

Tested Applications Application Description
Tested Reactivity human, mouse, rat, pig
Immunogen SOD2 fusion protein Ag21388 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name superoxide dismutase 2, mitochondrial
Synonyms SODM, MNSOD, Mn SOD, IPOB, IPO B
Calculated Molecular Weight 25 kDa
Observed Molecular Weight 25 kDa
GenBank Accession NumberBC016934
Gene Symbol SOD2
Gene ID (NCBI) 6648
RRIDAB_2883341
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP04179
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SOD2(superoxide dismutase 2, mitochondrial ) is also named as IPOB, MNSOD, SODM, Mn-SOD and belongs to the iron/manganese superoxide dismutase family. It is a marker of mitochondria, which is restricted to the perinuclear area in a cell with aggregate formation of mutant SOD1(PMID:12659845). It functions as the first line of antioxidant defense against highly reactive superoxide radicals and it appears to be early predictors for survival in septic patients with with MIF(PMID:20863520). It has 2 isoforms with the molecular weight of 25 kDa and 21 kDa.