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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 68651-1-Ig (same clone as 68651-1-PBS)

    WB analysis using 68651-1-Ig (same clone as 68651-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68651-1-Ig (SORL1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68651-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse cerebellum using 68651-1-Ig (same clone as 68651-1-PBS)

    IF Staining of mouse cerebellum using 68651-1-Ig (same clone as 68651-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse cerebellum tissue using SORL1 antibody (68651-1-Ig, Clone: 2E7D9 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) (SA00013-1). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68651-1-PBS in a different storage buffer formulation.

SORLA Monoclonal antibody, PBS Only

SORLA Monoclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 68651-1-PBS

产品说明书

CloneNo. 2E7D9

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IF-P, Indirect ELISA

别名

SORL1, SORL 1, Low-density lipoprotein receptor relative with 11 ligand-binding repeats, LDLR relative with 11 ligand-binding repeats, C11orf32

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy SORL1 Ready-To-Use IHC Kit. SORL1 primary antibody included.

产品信息

68651-1-PBS targets SORLA in WB, IF-P, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 human
免疫原 SORLA fusion protein Ag18445 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 sortilin-related receptor, L(DLR class) A repeats-containing
别名 SORL1, SORL 1, Low-density lipoprotein receptor relative with 11 ligand-binding repeats, LDLR relative with 11 ligand-binding repeats, C11orf32
计算分子量 2214 aa, 248 kDa
观测分子量 300 kDa
GenBank蛋白编号BC137171
基因名称 SORLA
Gene ID (NCBI) 6653
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ92673
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SorLA also known as SorL1 or LR11, is a multiligand receptor belonging to the LDL receptor superfamily. It is also a member of vacuolar protein sorting-10 (Vps10) family and is enriched in the brain. SorLA acts as an sorting receptor for APP and prevents amyloidogenic processing of APP. Downregulation of SorLA has been found in patients with sporadic Alzheimer disease (AD). Currently SorLA has emerged as a potential target for AD therapy. (25404298)