CoraLite®594-conjugated IL-1RL1/ST2 Polyclonal antibody

IL-1RL1/ST2 Polyclonal Antibody for FC (Intra)
Cat No. CL594-30194

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC (Intra)

IL1RL1, IL-33R, IL-1RL1, FIT 1, EC:3.2.2.6

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite®594
规格: 

-/ -


经过测试的应用

Positive FC (Intra) detected inHEK-293 cells
Planning an IHC experiment? We recommend our IHCeasy IL1RL1/ST2 Ready-To-Use IHC Kit. IL1RL1/ST2 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 30194-1-AP

推荐稀释比

应用推荐稀释比
Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.80 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-30194 targets IL-1RL1/ST2 in FC (Intra) applications and shows reactivity with human samples.

经测试应用 FC (Intra) Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 interleukin 1 receptor-like 1
别名 IL1RL1, IL-33R, IL-1RL1, FIT 1, EC:3.2.2.6
计算分子量 63 kDa, 37 kDa, 30 kDa
GenBank蛋白编号BC030975
基因名称 IL1RL1
Gene ID (NCBI) 9173
RRIDAB_3673431
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ01638
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ST2, also known as IL1RL1, is a member of the IL-1 superfamily and serves as the receptor for IL-33. It plays a major role in immune and inflammatory responses. ST2 is expressed by various types of immune cells including Th2 cells, mast cells, type 2 innate lymphoid cells, eosinophils, basophils, NK cells, and non-immune cells, including cardiomyocytes. Two forms of ST2 exist: a membrane-bound form and a soluble form (sST2). The membrane-bound form activates the MyD88/NF-κB signaling pathway to enhance mast cell, Th2, regulatory T cell (Treg), and innate lymphoid cell type 2 functions. sST2 acts as a decoy receptor. (PMID: 27055914; 23999434; 28484466)

实验方案

Product Specific Protocols
FC protocol for CL594 IL-1RL1/ST2 antibody CL594-30194Download protocol
Standard Protocols
Click here to view our Standard Protocols
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