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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated STOML2 Polyclonal antibody

STOML2 Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-10348

Print datasheet

Synonyms

SLP2, SLP 2, Paratarg-7, Paraprotein target 7, EPB72-like protein 2

验证数据展示

  • IF Staining of HeLa using CL488-10348

    IF Staining of HeLa using CL488-10348

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite® Plus 488 STOML2 antibody (CL488-10348) at dilution of 1:200.

  • IF Staining of HeLa using CL488-10348

    IF Staining of HeLa using CL488-10348

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite® Plus 488 STOML2 antibody (CL488-10348) at dilution of 1:200, CL594-Phalloidin (red).

经过测试的应用

Positive IF/ICC detected inHeLa cells
For other applications, we recommend the unconjugated version of this antibody, 10348-1-AP

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-10348 targets STOML2 in IF/ICC applications and shows reactivity with human, mouse, rat samples.

Tested Applications IF/ICC Application Description
Tested Reactivity human, mouse, rat
Immunogen STOML2 fusion protein Ag0363 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name stomatin (EPB72)-like 2
Synonyms SLP2, SLP 2, Paratarg-7, Paraprotein target 7, EPB72-like protein 2
Calculated Molecular Weight 356 aa, 39 kDa
Observed Molecular Weight 39 kDa
GenBank Accession NumberBC002442
Gene Symbol STOML2
Gene ID (NCBI) 30968
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UJZ1
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

STOML2 (Stomatin-like protein 2; also known as SLP-2) is a widely expressed mitochondrial member of the highly conserved family of stomatin proteins. STOML2 is localized mostly in mitochondrial inner membrane, minor in plasma membrane. Human STOML2 interacts with prohibitins and regulates mitochondrial biogenesis and function (21746876). In addition, plenty of studies revealed that STOML2 was overexpressed in many human cancer tissues, and its expression may be a new valuable prognostic biomarker (19839737, 21960069). Recently STOML2 has been identified as a serological biomarker for early colorectal cancer (CRC) diagnosis (21209152). Two isoforms of STOML2 exist due to the alternative splicing, with MW of 39 kDa and 33 kDa, respectively.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 STOML2 antibody CL488-10348Download protocol
Standard Protocols
Click here to view our Standard Protocols