CoraLite® Plus 488 Anti-Mouse TCR Beta (H57-597)

TCR Beta Monoclonal Antibody for IF/ICC, FC
Cat No. CL488-65106

产品说明书

CloneNo. H57-597

宿主/亚型

Armenian Hamster / IgG

种属反应性

Mouse

应用

IF/ICC, FC and More (1)

T cell receptor beta chain, TCR Beta, Tcrb, TCRβ, Tib

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inmouse splenocytes
Positive FC detected inmouse splenocytes
For other applications, we recommend the unconjugated version of this antibody, 65106-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:150-1:600
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IFSee 1 publications below

产品信息

CL488-65106 targets TCR Beta in IF/ICC, FC applications and shows reactivity with Mouse samples.

经测试应用 IF/ICC, FC Application Description
文献引用应用IF
经测试反应性 Mouse
免疫原 Affinity purified TCR from mouse DO-11.10 cells 种属同源性预测
宿主/亚型 Armenian Hamster / IgG
抗体类别 Monoclonal
产品类型 Antibody
全称 T-cell receptor beta chain
别名 T cell receptor beta chain, TCR Beta, Tcrb, TCRβ, Tib
基因名称 TCR beta
Gene ID (NCBI) 21577
RRIDAB_2883180
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Affinity purification
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 TCR Beta antibody CL488-65106Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
IF

Sci Adv

Stimulator of interferon gene facilitates recruitment of effector CD8 T cells that drive neurofibromatosis type 1 nerve tumor initiation and maintenance

Authors - Jay Pundavela
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