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CoraLite® Plus 488-conjugated TERF2IP Polyclonal antibody

TERF2IP Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-14595

Print datasheet

Synonyms

DRIP5, hRap1, RAP1 homolog, TERF2IP

验证数据展示

  • IF Staining of HeLa using CL488-14595

    IF Staining of HeLa using CL488-14595

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite® Plus 488 TERF2IP antibody (CL488-14595) at dilution of 1:200, CL594-phalloidin (red).

经过测试的应用

Positive IF/ICC detected inHeLa cells
Planning an IHC experiment? We recommend our IHCeasy TERF2IP Ready-To-Use IHC Kit. TERF2IP primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 14595-1-AP

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-14595 targets TERF2IP in IF/ICC applications and shows reactivity with human samples.

Tested Applications IF/ICC Application Description
Tested Reactivity human
Immunogen TERF2IP fusion protein Ag6130 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name telomeric repeat binding factor 2, interacting protein
Synonyms DRIP5, hRap1, RAP1 homolog, TERF2IP
Calculated Molecular Weight 44 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC005841
Gene Symbol TERF2IP
Gene ID (NCBI) 54386
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen Affinity Purified
UNIPROT IDQ9NYB0
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TERF2IP, also named as DRIP5, RAP1, is a 399 amino acid protein, which belongs to the RAP1 family. TERF2IP associates with chromosomes, both at telomeres and in extratelomeric sites. TERF2IP acts both as a regulator of telomere function and as a transcription regulator. TERF2IP is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. The calculated molecular weight of TERF2IP is 44 kDa, but modified TERF2IP, is about 60 kDa. (PMID: 15838871)

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 TERF2IP antibody CL488-14595Download protocol
Standard Protocols
Click here to view our Standard Protocols