验证数据展示
产品信息
84408-4-PBS targets TFDP2 in IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | IF/ICC, FC (Intra), Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | TFDP2 fusion protein Ag2054 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | transcription factor Dp-2 (E2F dimerization partner 2) |
别名 | Transcription factor Dp-2, DP2, Dp 2, 241457A12 |
计算分子量 | 446 aa, 49 kDa |
GenBank蛋白编号 | BC021113 |
基因名称 | TFDP2 |
Gene ID (NCBI) | 7029 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q14188 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TFDP2, also known as E2FDP2, is a coactivator of E2F factors and involves in EGF or IFN-gamma-mediated effects by enhancing or reducing active heterodimeric complexes. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis [PMID:16360038]. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of several genes whose products are involved in cell cycle regulation or DNA replication [PMID:16721044].