验证数据展示
产品信息
84408-4-PBS targets TFDP2 in IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | IF/ICC, FC (Intra), Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | TFDP2 fusion protein Ag2054 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | transcription factor Dp-2 (E2F dimerization partner 2) |
Synonyms | Transcription factor Dp-2, DP2, Dp 2, 241457A12 |
Calculated Molecular Weight | 446 aa, 49 kDa |
GenBank Accession Number | BC021113 |
Gene Symbol | TFDP2 |
Gene ID (NCBI) | 7029 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q14188 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TFDP2, also known as E2FDP2, is a coactivator of E2F factors and involves in EGF or IFN-gamma-mediated effects by enhancing or reducing active heterodimeric complexes. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis [PMID:16360038]. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of several genes whose products are involved in cell cycle regulation or DNA replication [PMID:16721044].