验证数据展示
经过测试的应用
Positive IF/ICC detected in | U2OS cells |
Positive FC (Intra) detected in | A431 cells |
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
84408-4-RR targets TFDP2 in IF/ICC, FC (Intra), ELISA applications and shows reactivity with human samples.
Tested Applications | IF/ICC, FC (Intra), ELISA Application Description |
Tested Reactivity | human |
Immunogen | TFDP2 fusion protein Ag2054 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | transcription factor Dp-2 (E2F dimerization partner 2) |
Synonyms | Transcription factor Dp-2, DP2, Dp 2, 241457A12 |
Calculated Molecular Weight | 446 aa, 49 kDa |
GenBank Accession Number | BC021113 |
Gene Symbol | TFDP2 |
Gene ID (NCBI) | 7029 |
RRID | AB_3671937 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q14188 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TFDP2, also known as E2FDP2, is a coactivator of E2F factors and involves in EGF or IFN-gamma-mediated effects by enhancing or reducing active heterodimeric complexes. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis [PMID:16360038]. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of several genes whose products are involved in cell cycle regulation or DNA replication [PMID:16721044].
实验方案
Product Specific Protocols | |
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IF protocol for TFDP2 antibody 84408-4-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |