CoraLite® Plus 488-conjugated TFF2 Polyclonal antibody

TFF2 Polyclonal Antibody for IF-P
Cat No. CL488-13681

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IF-P

SML1, SP, Spasmolysin, Spasmolytic polypeptide, TFF2, trefoil factor 2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive IF-P detected inmouse stomach tissue
For other applications, we recommend the unconjugated version of this antibody, 13681-1-AP

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-13681 targets TFF2 in IF-P applications and shows reactivity with human, mouse samples.

经测试应用 IF-P Application Description
经测试反应性 human, mouse
免疫原 TFF2 fusion protein Ag4537 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 trefoil factor 2
别名 SML1, SP, Spasmolysin, Spasmolytic polypeptide, TFF2, trefoil factor 2
计算分子量 129 aa, 14 kDa
观测分子量 18-20 kDa
GenBank蛋白编号BC032820
基因名称 TFF2
Gene ID (NCBI) 7032
RRIDAB_3083945
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ03403
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The trefoil factor family (TFF), comprises of three polypeptides, TFF1, TFF2 and TFF3 (7-12 kDa), secreted to mucosal surfaces by mucus producing cells, prominently in the gastrointestinal tract. TFF2, also known as spasmolytic polypeptide, is a low-molecular weight protein, expressed in mucous neck cells of the fundus and glands at the base of the antrum in normal human stomach. TFF2 could Inhibit gastrointestinal motility and gastric acid secretion. However, recent studies suggest that TFF2 could also play an important role in the immune system. We got a 18-20 kDa band in western botting maybe due to glycosylatation, and mature TFF2 is a 12 kDa protein (PMID: 10716671).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 TFF2 antibody CL488-13681Download protocol
Standard Protocols
Click here to view our Standard Protocols
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