验证数据展示
经过测试的应用
Positive FC detected in | Balb/c mouse peritoneal macrophages |
推荐稀释比
应用 | 推荐稀释比 |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
98018-1-RR targets TLR4/CD284 in FC applications and shows reactivity with mouse samples.
经测试应用 | FC Application Description |
经测试反应性 | mouse |
免疫原 | TLR4/CD284 fusion protein Ag32998 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | toll-like receptor 4 |
别名 | Tlr4, CD284, toll like receptor 4, 230463C7 |
计算分子量 | 96 kDa |
GenBank蛋白编号 | NM_021297 |
基因名称 | Tlr4 |
Gene ID (NCBI) | 21898 |
RRID | AB_3672162 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q9QUK6 |
储存缓冲液 | PBS with 0.09% sodium azide , pH 7.3 |
储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
实验方案
Product Specific Protocols | |
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FC protocol for TLR4/CD284 antibody 98018-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |